Research Article
Infiltration of Blood-Derived Macrophages Contributes to the Development of Diabetic Neuropathy
Figure 3
Hyperglycemia increases the infiltration of blood-derived macrophages in the spinal cord. (a, b) Examples of flow cytometry analysis of the spinal cord are shown, identifying monocyte-derived macrophages (MDMs) and microglia as CD45+CD11bhigh and CD45+CD11blow, respectively. (c) Spontaneous infiltration of circulating monocytes to the spinal cord increases after STZ injection. Numbers of animals: control, ; D7, ; D14, ; D28, . Mann-Whitney test was used. Data are means SEMs; vs. control.
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