Analysis of Genetic Variation in CD40 and CD40L: Relationship with mRNA Relative Expression and Soluble Proteins in Acute Coronary Syndrome
Table 3
Genotype and allele frequency of the CD40L rs3092952 and rs3092920 in the ACS and CG by gender.
ACS (%)
CG (%)
OR (CI 95%)
a
rs3092952
MAF
Allele
Male
A
115 (46.7)
89 (54.9)
1.39 (0.93-2.07)
0.11
0.50
0.73
G
131 (53.3)
73 (45.1)
Allele
Female
A
68 (45.9)
154 (50)
1.18 (0.79-1.74)
0.42
0.51
G
80 (54.1)
154 (50)
Genotype
Female
A/A
18 (24.3)
37 (24)
1
-
A/G
32 (43.2)
80 (52)
0.82 (0.41-1.65)
0.58
-
-
G/G
24 (32.5)
37 (24)
1.33 (0.62-2.86)
0.46
rs3092920
MAF
Allele
Male
G
197 (80)
138 (85.2)
1.43 (0.84-2.44)
0.19
0.180
0.96
T
49 (20)
24 (14.8)
Allele
Female
G
120 (81)
253 (82.1)
0.93 (0.56-1.54)
0.78
0.182
T
28 (19)
55 (17.9)
Genotype
Female
G/G
48 (64.9)
104 (67.5)
1
-
-
-
G/T
24 (32.4)
45 (29.2)
0.86 (0.47-1.58)
0.64
T/T
2 (2.7)
5 (3.3)
1.15 (0.22-6.16)
0.87
ACS: acute coronary syndrome; CG: control group; CI: confidence interval; MAF: minor allele frequencies; OR: odds ratio. a value for the allelic model between genders.
