High Thymic Output of Effector CD4+ Cells May Lead to a Treg : T Effector Imbalance in the Periphery in NOD Mice
Percentages and absolute numbers of CD4+Foxp3+ cells are not decreased in the thymus in NOD compared to B6 mice at either 4 or 9 weeks of age. Thymocytes were collected from NOD or B6 mice at (a, c) 4 or (b, d) 9 weeks of age and evaluated for the percentages (a, b) and absolute numbers (c, d) of CD4+Foxp3+ cells. Each symbol represents data from an individual animal. denotes a significant difference at .