Skin-Resident γδ T Cells Exhibit Site-Specific Morphology and Activation States

Figure 1

Fluorescent immunohistochemical analysis of skin-resident γδ T cells in whole-mount tissue. Skin obtained from the murine ear, back, and footpad was stained using anti-TCRγ/δ antibody and visualized using whole-mount immunofluorescence. There appear to be greater numbers of γδ T cells, with more stellate morphology, in the ear (a, d) and back (b, e) than in the footpad (c, f). Cells in the footpad have a more rounded appearance, with fewer processes emanating from the cell body. Scale bars = 50 μm.