Research Article
Immunogenic Evaluation of Ribosomal P-Protein Antigen P0, P1, and P2 and Pentameric Protein Complex P0-(P1-P2)2 of Plasmodium falciparum in a Mouse Model
Figure 7
Humoral response after threefold immunization with the recombinant ribosomal P. falciparum proteins. Two weeks after each vaccination (denoted here as I, II, and III), the levels of antibodies were measured: total IgG (a), IgG1 (b), and IgG2a (c). The antibody titer was characterized as the reciprocal of the highest serum dilution factor corresponding to a mean absorbance value of 0.1. Each data is presented as the of six mice. The differences were analyzed statistically with the Kruskal-Wallis test followed by the Dunn multiple comparison test. Significantly different from (+) the first immunization or (++) the second immunization with the same protein, .
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