Figure 1: STAT3 rs744166 risky allele “A” positively correlates with surgery numbers in Crohn’s disease patients. Patients in this study suffered stricture and fistula at various sites of the gastrointestinal tract. The locations of strictures was shown in (a), and (b) demonstrated various locations of fistula in this cohort of patients. (c) The correlation of surgery numbers and carriage of risky allele “A” was tested by a GENMOD procedure in SAS with the adjustment of age of diagnosis. Different surgery numbers were represented as different colors.