Integrative Analyses of Genes Associated with Fulminant Type 1 Diabetes

Table 1

The results of Gene Ontology (GO) of DEGs ranked by value.

Term	Count	value	Genes
GO-BPs
Generation of precursor metabolites and energy	4	0.004	AVP, UQCR11, COX7C, COX6C
Hydrogen ion transmembrane transport	4	0.006	NDUFA4, UQCR11, COX7C, COX6C
Mitochondrial electron transport, cytochrome c to oxygen	3	0.006	NDUFA4, COX7C, COX6C
Extrinsic apoptotic signaling pathway in the absence of ligand	3	0.017	MOAP1, ERBB3, ITGAV
Positive regulation of female receptivity	2	0.018	NCOA1, OXT
Positive regulation of gene expression	6	0.02	AMH, ATF4, AVP, LDLR, ERBB3, GPER1
Maternal aggressive behavior	2	0.024	AVP, OXT
Hyperosmotic salinity response	2	0.029	AVP, OXT
Cellular response to lipopolysaccharide	4	0.03	TNFRSF1B, ADAMTS13, PAF1, CACTIN
Social behavior	3	0.033	AVP, OXT, DLG4
Positive regulation of apoptotic process	6	0.034	MOAP1, ATF4, NCOA1, ARHGEF6, GPER1, PDCD1
Male mating behavior	2	0.035	NCOA1, OXT
Positive regulation of uterine smooth muscle contraction	2	0.041	OXT, GPER1
Drinking behavior	2	0.041	HTR1B, OXT
Positive regulation of cytosolic calcium ion concentration	4	0.046	AVP, OXT, DLG4, GPER1
GO-MFs
Neurohypophyseal hormone activity	2	0.011	AVP, OXT
Cytochrome c oxidase activity	3	0.013	NDUFA4, COX7C, COX6C
Neuregulin binding	2	0.028	ERBB3, ITGAV
GO-CCs
Mitochondrial inner membrane	8	0.014	NDUFA4, UQCR11, SLC25A25, COX7C, ROMO1, MRPL30, NDUFB1, COX6C
Extracellular space	14	0.046	INA, AVP, CXCL5, ERBB3, ADAMTS13, OXT, FETUB, AMH, IFNAR2, C1QTNF5, CLEC3B, CD59, SEMA4D, PRSS33
Cell junction	7	0.05	CNIH2, OTOF, PRRT1, DLG4, PAF1, GPER1, GPR142