Research Article

Anti-Tyro3 IgG Associates with Disease Activity and Reduces Efferocytosis of Macrophages in New-Onset Systemic Lupus Erythematosus

Table 1

The clinical and laboratory characteristics of new-onset and treatment-naïve SLE patients.

VariableSLE patients

Gender (female/male, )60/10
Age (, years)
Disease duration (months, median, IQR)3.5 (1, 24)
SLEDAI ()
Fever (, %)32 (45.7)
Arthritis (, %)42 (60.0)
Rash (, %)36 (51.4)
Oral ulcer (, %)16 (22.9)
Alopecia (, %)16 (22.9)
Vasculitis (, %)5 (7.1)
Serositis (, %)16 (22.9)
Photosensitivity (, %)10 (14.3)
Raynaud’s phenomenon (, %)13 (18.6)
Hematological (, %)54 (77.1)
Lupus nephritis ( g/24 h) (, %)31 (44.3)
Neuropsychiatric manifestations (, %)1 (1.4)
Anti-dsDNA positive (, %)63 (90.0)
Anti-Sm positive (, %)17 (24.3)
Anti-SSA positive (, %)38 (54.3)
Anti-SSB positive (, %)8 (11.4)
Anti-U1RNP positive (, %)27 (38.6)
Anti-Rib-P positive (, %)29 (41.4)
Anti-nucleosome-A positive (, %)24 (34.3)

Note: SD: standard deviation; SLE: systemic lupus erythematosus; SLEDAI: SLE disease activity index; IQR: interquartile range; dsDNA: double-stranded DNA.