Research Article

Indoleamine 2,3-Dioxygenase (IDO) Expression Is an Independent Prognostic Marker in Esophageal Adenocarcinoma

Figure 4

(a) High amounts of CD3-positive T cells are associated with an improved OS in esophageal adenocarcinoma. (b) Tumors with IDO-positive TILs show better median overall survival of 47.7 months in IDO-positive tumors compared to a median OS of 22.7 months for IDO-negative tumors. (c) In the pT1/2 group, patients with IDO-positive expression have a calculated average OS of 142.1 months (median not reached) compared to an average OS of 37.1 months (median OS 30.5 months), . (d) The survival difference remains significant also in the subgroup of pT3/4 tumor stages with median OS of 33.3 months for IDO-positive tumors and 22.1 months for IDO-negative tumors ().