Indoleamine 2,3-Dioxygenase (IDO) Expression Is an Independent Prognostic Marker in Esophageal Adenocarcinoma

Table 1

Patient characteristics and IDO expression results on the test cohort (; 159 analyzable).

			IDO expression surface margin					IDO expression infiltration margin
			Negative		Positive		value	Negative			Positive	value
	No.	%	No.	%	No.	%		No.	%	No.	%
Sex
Female	16	10.1%	5	31.3%	11	68.7%	0.430	5	33.3%	10	66.7%	0.783
Male	143	89.9%	62	43.4%	81	56.6%		58	41.1%	83	58.9%
Age group
<65 years	70	44.3%	31	44.3%	39	55.7%	0.746	31	45.6%	37	54.4%	0.248
>65 years	88	55.7%	36	77.0%	52	23.0%		31	35.6%	56	64.4%
Tumor stage
pT1	46	29.1%	13	28.3%	33	71.7%	0.070	13	29.5%	31	70.5%	0.200
pT2	29	18.4%	12	41.4%	27	58.6%		11	37.9%	18	62.1%
pT3	82	51.9%	41	50.0%	41	50.0%		37	45.7%	44	54.3%
pT4	1	0.6%	1	100%	0	0.0%		1	100%	0	0.0%
Lymph node metastasis
pN0	60	38.0	17	23.3%	43	71.75	0.022	20	33.9%	39	66.1%	0.154
pN1	71	44.9	34	47.9%	37	52.1%		26	37.0%	43	62.3%
pN2	12	7.6	6	50.0%	6	50.0%		7	58.3%	5	41.7%
pN3	15	9.55	10	66.6%	5	33.3%		9	60.0%	6	40.0%
UICC stage
I	41	26.1%	21	51.2%	20	48.8%	<0.001	23	57.6%	17	42.5%	0.045
II	21	13.4%	15	71.4%	6	28.6%		14	66.7%	7	33.3%
III	75	47.8%	69	92.0%	6	8.0%		60	78.9%	16	21.1%
IV	20	12.7%	17	85.9%	3	15.0%		17	85.0%	3	15.0%