Journal of Immunology Research / 2020 / Article / Tab 1

Research Article

Circulating Neutrophils of Nonalcoholic Steatohepatitis Patients Show an Activated Phenotype and Suppress T Lymphocytes Activity

Table 1

Anthropometric and biochemical parameters in healthy donors, NAFL, and NASH patients.

ParametersHealthy donors (10)NAFL (10)NASH (20) value (NASH vs. healthy donors) value (NASH vs. NAFL)

Age (years)0.16820.8655
Sex (F/M)5/54/612/8
Weight (kg)<0.0001<0.0001
BMI (kg/m2)<0.0001<0.0001
AST (UI/mL)0.00460.0007
ALT (UI/mL)0.00060.0005
GGT (UI/mL)<0.0001<0.0001
Total cholesterol (mg/dL)<0.0001<0.0001
LDL cholesterol (mg/dL)0.04320.0339
HDL cholesterol (mg/dL)0.78020.1406
Triglycerides (mg/dL)0.01690.0004
Glucose (mg/dL)0.02640.0173
Insulin (UI/mL)<0.0001<0.0001
Alkaline phosphatase (UI/L)0.30440.0923
Total bilirubin (mg/dL)0.18830.9803
Direct bilirubin (mg/dL)0.05240.5823
HOMA-IR<0.0001<0.0001
SBP (mmHg)0.22680.0684
DBP (mmHg)0.0072< 0.0001
Leucocyte (103/μL)0.03590.0586
Neutrophil (103/μL)0.00020.0003
Lymphocyte (103/μL)0.69810.3611
NLR0.00210.0093

BMI: body mass index; AST: aspartate aminotransferase; ALT: alanine aminotransferase; GGT: Gamma glutamil transferase; HOMA-IR: homeostasis model assessment of insulin resistance; LDL: Low Density Lipoprotein; HDL: High Density Lipoprotein; SBP: systolic blood pressure; DBP: systolic blood pressure; NLR: Neutrophil-to-lymphocyte ratio. Normally distributed date described as mean, standard deviations (SDs), value, , , , , and unpaired Mann-Whitney test.

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