Linking Complement C3 and B Cells in Nasal Polyposis
Complement C3 is located at epithelial cells in the nasal region. (a) The distribution of complement C3 was examined for nasal polyps and inferior turbinate with LSAB stainings. Example pictures are shown (bar is 200 μm). (b) Using flow cytometry analysis, CD45-/EpCAM+/pan-Keratin+ cells were evaluated for MFI of AlexaFluor488® (C3, AF488) in a single cell suspension from primary CRSwNP patient tissues, corresponding inferior turbinates () and nasal polyps (). Means with SEM are shown.
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