Research Article

Early sST2 Liberation after Implantation of a Left Ventricular Assist Device in Patients with Advanced Heart Failure

Table 1

Baseline characteristics of the study population ().

Variables
1-year survivors ()1-year nonsurvivors () value

Age (y)59 (56-69)64 (60-69)0.21a
BMI (kg/m2)24.7 (22.7-29)24.9 (22.8-34.4)0.55a
Female4 (30.8)2 (28.6)0.92b
Ntpro-BNP (pg/ml)6094 (3856-6818)5492 (1918-15000)0.84a
INTERMACS level0.83b
 I1 (7.6)1 (14.3)
 II3 (23)1 (14.3)
 III7 (53.8)3 (42.9)
 IV2 (15.3)2 (28.6)
Therapeutic intent
 Bridge to decision0 (0)1 (14.3)
 Bridge to candidacy8 (61.5)4 (57.1)
 Bridge to transplant1 (7.7)0 (0)
 Destination therapy4 (30.8)2 (28.6)
Diabetes0.37b
 NIDDM0 (0)1 (14.3)
 IDDM4 (30.8)2 (28.6)
History of arterial hypertension9 (69.2)4 (57.1)0.58b
CHA2DS2-VASc score3 (3-4)3 (2-5)1a
Malignant arrhythmia2 (15.3)1 (14.3)0.94b
COLD6 (46.2)1 (14.3)0.32b
Renal insufficiency (including patients on HF)9 (69.2)3 (42.9)0.35b
Creatinine (mg/dl)1.25 (0.91-1.4)1.04 (1.01-1.8)0.6a
Left ventricular ejection fraction (%)20 (15-25)20 (15-25)0.93a
Systolic PAP (mmHg)59 (45-67)47 (38-57)0.21a
Types of cardiomyopathy (CMP)0.58b
 Ischemic CMP9 (69.2)4 (57.1)
 Dilated CMP4 (30.8)3 (42.9)

Values are medians with interquartile ranges (IQRs) or absolute numbers (percentages); aMann–Whitney test, bFisher exact or chi-square test. BMI = body mass index; BNP = brain natriuretic peptide; INTERMACS = Interagency Registry for Mechanically Assisted Circulatory Support; NIDDM = non-insulin-dependent diabetes mellitus; CHA2DS2-VASc score = congestive heart failure, hypertension, , diabetes, prior, stroke/transient ischemic attack; IDDM = insulin-dependent diabetes mellitus; COLD = chronic obstructive lung disease; HF = hemofiltration; PAP = pulmonary artery pressure.