Research Article
Early sST2 Liberation after Implantation of a Left Ventricular Assist Device in Patients with Advanced Heart Failure
Table 1
Baseline characteristics of the study population (
).
| Variables | | 1-year survivors () | 1-year nonsurvivors () | value |
| Age (y) | 59 (56-69) | 64 (60-69) | 0.21a | BMI (kg/m2) | 24.7 (22.7-29) | 24.9 (22.8-34.4) | 0.55a | Female | 4 (30.8) | 2 (28.6) | 0.92b | Ntpro-BNP (pg/ml) | 6094 (3856-6818) | 5492 (1918-15000) | 0.84a | INTERMACS level | | | 0.83b | I | 1 (7.6) | 1 (14.3) | | II | 3 (23) | 1 (14.3) | | III | 7 (53.8) | 3 (42.9) | | IV | 2 (15.3) | 2 (28.6) | | Therapeutic intent | | | | Bridge to decision | 0 (0) | 1 (14.3) | | Bridge to candidacy | 8 (61.5) | 4 (57.1) | | Bridge to transplant | 1 (7.7) | 0 (0) | | Destination therapy | 4 (30.8) | 2 (28.6) | | Diabetes | | | 0.37b | NIDDM | 0 (0) | 1 (14.3) | | IDDM | 4 (30.8) | 2 (28.6) | | History of arterial hypertension | 9 (69.2) | 4 (57.1) | 0.58b | CHA2DS2-VASc score | 3 (3-4) | 3 (2-5) | 1a | Malignant arrhythmia | 2 (15.3) | 1 (14.3) | 0.94b | COLD | 6 (46.2) | 1 (14.3) | 0.32b | Renal insufficiency (including patients on HF) | 9 (69.2) | 3 (42.9) | 0.35b | Creatinine (mg/dl) | 1.25 (0.91-1.4) | 1.04 (1.01-1.8) | 0.6a | Left ventricular ejection fraction (%) | 20 (15-25) | 20 (15-25) | 0.93a | Systolic PAP (mmHg) | 59 (45-67) | 47 (38-57) | 0.21a | Types of cardiomyopathy (CMP) | | | 0.58b | Ischemic CMP | 9 (69.2) | 4 (57.1) | | Dilated CMP | 4 (30.8) | 3 (42.9) | |
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Values are medians with interquartile ranges (IQRs) or absolute numbers (percentages); aMann–Whitney test, bFisher exact or chi-square test. BMI = body mass index; BNP = brain natriuretic peptide; INTERMACS = Interagency Registry for Mechanically Assisted Circulatory Support; NIDDM = non-insulin-dependent diabetes mellitus; CHA2DS2-VASc score = congestive heart failure, hypertension, , diabetes, prior, stroke/transient ischemic attack; IDDM = insulin-dependent diabetes mellitus; COLD = chronic obstructive lung disease; HF = hemofiltration; PAP = pulmonary artery pressure. |