Research Article
Prealbumin-to-Globulin Ratio Can Predict the Chemotherapy Outcomes and Prognosis of Patients with Gastric Cancer Receiving First-Line Chemotherapy
Table 2
Relationship between the pretreatment PGR and AGR and clinicopathological factors.
| | PGR | AGR | Low | High | value | Low | High | value |
| Sex | | | | | | | Male | 95 | 92 | 0.528 | 86 | 101 | 0.835 | Female | 44 | 50 | 42 | 52 | Age (yr) | | | | | | | >60 | 63 | 59 | 0.523 | 61 | 61 | 0.190 | ≤60 | 76 | 83 | 67 | 92 | Body mass index (kg/m2) | | | | | | | <18.5 or >25 | 40 | 32 | 0.231 | 30 | 42 | 0.443 | 18.5–25 | 99 | 110 | 98 | 111 | ECOG | | | | | | | 0–1 | 113 | 120 | 0.474 | 104 | 129 | 0.497 | ≥2 | 26 | 22 | 24 | 24 | Histological type | | | | | | | Papillary, tubular | 35 | 38 | 0.763 | 27 | 46 | 0.088 | Poorly cohesive, mucinous | 104 | 104 | 101 | 107 | TNM stage | | | | | | | III | 26 | 29 | 0.717 | 21 | 34 | 0.221 | IV | 113 | 113 | 107 | 119 | Number of organs affected by metastasis | | | | | | | 0–1 | 90 | 100 | 0.309 | 78 | 112 | 0.029 | ≥2 | 49 | 42 | 50 | 41 | Peritoneal metastasis | | | | | | | Yes | 52 | 39 | 0.075 | 50 | 41 | 0.029 | No | 87 | 103 | 78 | 112 | CEA (ng/mL) | | | | | | | >5 | 67 | 54 | 0.085 | 56 | 65 | 0.831 | ≤5 | 72 | 88 | 72 | 88 | CA72-4 (U/mL) | | | | | | | >6 | 79 | 79 | 0.839 | 76 | 82 | 0.331 | ≤6 | 60 | 63 | 52 | 71 | CA19-9 (U/mL) | | | | | | | >37 | 59 | 47 | 0.106 | 52 | 54 | 0.359 | ≤37 | 80 | 95 | | 76 | 99 | | Hemoglobin (g/L) | | | | | | | <115 | 63 | 42 | 0.006 | 61 | 44 | 0.001 | ≥115 | 76 | 100 | 67 | 109 |
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PGR: prealbumin-to-globulin ratio; AGR: albumin-to-globulin ratio; ECOG: Eastern Cooperative Oncology Group; TNM: tumor-node-metastasis; CEA: carcinoembryonic antigen; CA72-4: carbonhydrate antigen 72-4; CA 19-9: carbohydrate antigen 19-9.
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