Elevated Levels of Activated and Pathogenic Eosinophils Characterize Moderate-Severe House Dust Mite Allergic Rhinitis

Figure 2

The numbers of activated eosinophils are increased in moderate-severe allergic rhinitis. Gating strategies used to characterize the activated status of eosinophils in the peripheral blood (a) and nose (c). Percentages and absolute numbers of CD44- and CD69-expressing eosinophils in the peripheral blood (b) and nose (d). Data are presented as median with interquartile range. HC: healthy controls; M-AR: mild allergic rhinitis; MS-AR: moderate-severe allergic rhinitis; FMO: fluorescence minus one control.

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