Elevated Levels of Activated and Pathogenic Eosinophils Characterize Moderate-Severe House Dust Mite Allergic Rhinitis

Figure 6

Blood eosinophils derived from moderate-severe allergic rhinitis have a pro-Th2 capacity. (a) Representative flow plots and (b) quantification of IL-4 expression by CD4⁺ T cells obtained from healthy controls after coculture with blood eosinophils from healthy controls, mild allergic rhinitis, and moderate-severe allergic rhinitis for five days. HC: healthy controls; M-AR: mild allergic rhinitis; MS-AR: moderate-severe allergic rhinitis.

(a)

(b)