Elevated Levels of Activated and Pathogenic Eosinophils Characterize Moderate-Severe House Dust Mite Allergic Rhinitis

Table 3

Demographic summary of subjects in the cohort study.

	Healthy controls	Mild AR	Moderate-severe AR	value
Total subjects,	10	10	21	—
Gender, male/female	4/6	7/3	11/10	0.399
Age (years)	24 (22, 25)	25 (22, 26.25)	23 (22, 25.5)	0.552
History of smoking (%)	1 (10)	0	0	0.204
Intermittent/persistent	/	2/8	0/21	—
SPT to Der p	Negative	Positive	Positive	—
Total IgE (KU/l)	53.4 (28.7, 78.1)	99.9 (81.7, 118.1)	137.6 (82.2, 193)	0.000
Specific IgE to Der p (KU/l)	0.07 (0.04, 0.15)	23.0 (7.48, 47.53)	65.0 (13.65, 99.2)	0.000

For continuous variables, data are expressed by medians and interquartile ranges. AR: allergic rhinitis; SPT: skin prick test; Der p: Dermatophagoides pteronyssinus; Ig: immunoglobulin.