Review Article
The Application of Single-Cell RNA Sequencing in Vaccinology
Table 1
Summary of prophylactic vaccinology publications using scRNA-seq.
| Reference | Cell type | Species | Vaccine pathogen | scRNA-seq method |
| Afik et al. 2017. Nucleic Acids Res. [78] | CD8+ T cells | Human | Yellow fever | Smart-seq | Upadhyay et al. 2018. Genome Med. [80] | Plasmablasts | Human; Rhesus | Influenza; SIV | Smart-seq | Neu et al. 2019. J Clin Invest. [92] | Plasmablasts | Human | Influenza | Smart-seq/Spec-Seq | Cirelli et al. 2019. Cell. [81] | B cells | Rhesus | HIV | Smart-seq | Waickman et al. 2019. Nat Commun. [87] | CD8+ T cells | Human | Dengue | 10X | Sheerin et al. 2019. Sci Rep. [63] | Neutrophils | Mouse | Neisseria meningitidis serogroup B | 10X | Darrah et al. 2020. Nature. [133] | T cells | Rhesus | Tuberculosis | Seq-Well |
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