Review Article

The Application of Single-Cell RNA Sequencing in Vaccinology

Table 1

Summary of prophylactic vaccinology publications using scRNA-seq.

ReferenceCell typeSpeciesVaccine pathogenscRNA-seq method

Afik et al. 2017. Nucleic Acids Res. [78]CD8+ T cellsHumanYellow feverSmart-seq
Upadhyay et al. 2018. Genome Med. [80]PlasmablastsHuman; RhesusInfluenza; SIVSmart-seq
Neu et al. 2019. J Clin Invest. [92]PlasmablastsHumanInfluenzaSmart-seq/Spec-Seq
Cirelli et al. 2019. Cell. [81]B cellsRhesusHIVSmart-seq
Waickman et al. 2019. Nat Commun. [87]CD8+ T cellsHumanDengue10X
Sheerin et al. 2019. Sci Rep. [63]NeutrophilsMouseNeisseria meningitidis serogroup B10X
Darrah et al. 2020. Nature. [133]T cellsRhesusTuberculosisSeq-Well