Research Article

Development of an Immunoassay for the Detection of Amyloid Beta 1-42 and Its Application in Urine Samples

Table 2

Cross-reactivity of synthesized peptides and two beta amyloid proteins.

SampleSequence (ng/ml)% cross-reaction

Aβ1-42DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIA103.20100.00
Aβ1-8DAEFRHDS148.8069.40
Aβ1-40DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVV187.7055.00
Aβ7-15DSGYEVHHQ>4000-
Aβ14-21HQKLVFFA>4000-
Aβ20-27FAEDVGSN>4000-
Aβ26-33SNKGAIIG>4000-
Aβ32-39IGLMVGGV>4000-
Aβ35-42MVGGVVIA>4000-
Aβ36-43VGGVVIAT>4000-