Research Article

Upregulation of FOXO3 in New-Onset Type 1 Diabetes Mellitus

Table 1

Clinical characteristics of type 1 diabetes patients.

Clinical featuresT1DSevere T1D onsetMild T1D onset
(%) (%) (%)

Gender, F/M4/24
Age (y)
BMI (kg/m2)
HbA1c (%)
C peptide (nmol/l)
25-OH-D (ng/ml)
DKA12 (43)12 (100)16 (0)
IAA7 (25)3 (25)4 (25)
GADA21 (75)9 (75)12 (75)
IA2A23 (82)11 (92)12 (75)

BMI: body mass index; HbA1c: glycated haemoglobin A1c; 25-OH-D: 25-hydroxyvitamin D; DKA: diabetic ketoacidosis; IAA: antibodies to insulin; GADA: antibodies to glutamic acid decarboxylase; IA2A: antibodies to islet antigen-2; clinical features presented as ; number of subjects (%); , values estimated by unpaired -test, severe T1D onset vs. mild T1D onset subgroup.