Association of High Calcitriol Serum Levels and Its Hydroxylation Efficiency Ratio with Disease Risk in SLE Patients with Vitamin D Deficiency

Figure 3

Calcitriol serum levels and vitamin D hydroxylation efficiency ratio stratified by the calcidiol reference values. (a) Calcitriol serum levels (pg/mL) from SLE patients vs. HS, (b) Efficiency of vitamin D hydroxylation (pg/ng) from SLE patients vs. HS; (c) calcitriol serum levels (pg/mL) from SLE patients with clinical activity vs. SLE patients with clinical inactivity; (d) efficiency of vitamin D hydroxylation (pg/ng) from SLE patients with clinical activity vs. SLE patients with clinical inactivity; (e) calcitriol serum levels (pg/mL) from SLE patients with renal activity vs. SLE patients with no renal activity, (f) efficiency of vitamin D hydroxylation (pg/ng) from SLE patients with renal activity vs. SLE patients with no renal activity. Data provided in median, Mann–Whitney test. Calcidiol reference values: deficiency (<20 ng/mL), insufficiency (≥20 to <30 ng/mL), and sufficiency (≥30 ng/mL).