Human Adenovirus Serotype 3 Infection Modulates the Biogenesis and Composition of Lung Cell-Derived Extracellular Vesicles

Figure 2

Morphological characterization of HAdV3-infected A549-derived exosomes. (a) TEM analysis of HAdV3-infected A549-derived exosomes. Images showing morphologies of EVs isolated from uninfected and MOI 300. (b) NTA showing distribution pattern of uninfected EVs (c) at MOI 300. (d) The graph showing assessment of EVs’ mean particle sizes after 48 h of infection and (e) 72 h of infection. (f) The graph showing quantification of HAdV3-infected A549-derived EVs per mL after 48 h and (g) 72 h of infection. Data show the from four independent experiments. Data shows the from four independent experiments and performed using one-way analysis of variance (ANOVA) with Tukey post hoc analysis. Statistical significance is indicated by the as follows: , , , and .

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