Robust Plasma Cell Response to Skin-Inoculated Dengue Virus in Mice

Figure 3

PCs specific to DENV and structural E and prM proteins. ELISPOT assays of DENV-, E-, and prM-IgM and -IgG PCs were performed at day 10 postinoculation. Representative pictures of wells for the detection of total or DENV-specific IgM (a) and IgG SFU (b). Graphs showing the number of total and DENV-specific IgM (c) or IgG SFU (d) per DLN. Representative pictures of wells detecting E- and prM-specific IgM (e) or IgG SFU (f). Graphs showing the number of E- and prM-specific IgM (g) or IgG SFU (h). Data shown represent the of one experiment with 4 mice per group. Data were analyzed with the Mann–Whitney test. .

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