Research Article

circSLC6A6 Sponges miR-497-5p to Promote Endometrial Cancer Progression via the PI4KB/Hedgehog Axis

Figure 2

circSLC6A6 promotes EC cell proliferation, migration, and invasion in vitro. (a) The relative circSLC6A6 expression in HEC-1B cells transfected with si-circSLC6A6-1 and si-circSLC6A6-2, respectively, by qRT-PCR. (b) The relative circSLC6A6 expression in HEC-1A cells transfected with oe-circSLC6A6 vectors by qRT-PCR. (c) The proliferation abilities of HEC-1B cells transfected with si-circSLC6A6 and HEC-1A cells transfected with oe-circSLC6A6 were determined by the colony formation assay. (d) The proliferation abilities of HEC-1B cells transfected with si-circSLC6A6 and HEC-1A cells transfected with oe-circSLC6A6 were determined by the EdU assay. (e) Cell migration was detected by the wound healing assay in HEC-1B cells transfected with si-circSLC6A6 and HEC-1A cells transfected with oe-circSLC6A6. (f) Cell migration and invasion abilities of HEC-1B cells transfected with si-circSLC6A6 and HEC-1A cells transfected with oe-circSLC6A6 were detected by the transwell assay (, ).
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