Circular RNA ITCH Is a Tumor Suppressor in Clear Cell Renal Cell Carcinoma Metastasis through miR-106b-5p/PDCD4 Axis

Figure 1

circ-ITCH inhibits ccRCC cell migration and invasion. (a, b) The expression of circ-ITCH in ccRCC tissues and cells by qT-PCR. (c, d) Transwell assay determines the role of circ-ITCH in migration and invasion of OSRC-2 and SW839 cells. (e) Wound healing detects the effect of circ-ITCH downregulation on the migration abilities of OSRC-2 and SW839 cells. (f) The expressions of E-cadherin and N-cadherin in OSRC-2 and SW839 cells transfected with OE-circ-ITCH.

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