Recovery from Liver Failure and Fibrosis in a Rat Portacaval Anastomosis Model after Neurointermediate Pituitary Lobectomy

Figure 1

Experimental schedule. Rats were divided into intact control (IC), neurointermediate pituitary lobectomy (NIL), portacaval anastomosis (PCA), and the PCA+NIL groups. PCA and NIL surgeries were performed at weeks 0 and 3, respectively. At week 4, all animals were anesthetized, bled, and euthanized. Serum aliquots were used for assessing functional liver test, tissue liver samples were used to assess inflammatory and fibrogenic factors expression, histopathological studies and collagen and glycogen contents. animals/group.