Research Article
Development of Delivery Systems Enhances the Potency of Cell-Based HIV-1 Therapeutic Vaccine Candidates
Table 1
Different immunization strategies using MSCs, DCs, and proteins in BALB/c mice.
| Group | Modality | First injection | Second injection | Third injection |
| G1 | MSC/MSC/MSC | MSC (Nef DNA) ( cells) | MSC (Nef DNA) ( cells) | MSC (Nef DNA) ( cells) | G2 | MSC/protein/protein | MSC (Nef DNA) ( cells) | Nef protein+ Montanide (10 μg) | Nef protein+ Montanide (10 μg) | G3 | Protein/protein/protein | Nef protein+ Montanide (10 μg) | Nef protein+ Montanide (10 μg) | Nef protein+ Montanide (10 μg) | G4 | DC/DC/DC | DC (Nef DNA) ( cells) | DC (Nef DNA) ( cells) | DC (Nef DNA) ( cells) | G5 | DC/protein/protein | DC (Nef DNA) ( cells) | Nef protein+ Montanide (10 μg) | Nef protein+ Montanide (10 μg) | G6 | Control | Montanide | Montanide | Montanide | G7 | Control | PBS | PBS | PBS | G8 | Control | MSC | MSC | MSC | G9 | Control | DC | DC | DC |
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