Research Article
Therapeutic Mechanism and Effect of Camptothecin on Dextran Sodium Sulfate-Induced Ulcerative Colitis in Mice
Figure 5
Effects of camptothecin (CPT) on the AKT/NF-κB signaling pathway in DSS-induced ulcerative colitis in mice. Tissue lysates were prepared and subjected to western blot using (a, b) p-AKT, (a, c) p-IκBα, and (a, d) p-p65 antibodies. The p-AKT, p-p65, and p-IκBα immunoreactive bands were digitized and expressed as a ratio of AKT, IκBα, and p65 levels (b–d). Values are presented as (, , and vs. the LPS group).
(a) |
(b) |
(c) |
(d) |