IFI44L as a Forward Regulator Enhancing Host Antituberculosis Responses

Figure 2

IFI44L induced by M. tuberculosis H37Rv-infected macrophages. (a) IFI44L was significantly upregulated at 24 h in M. tuberculosis H37Rv-infected macrophage group. (b) Intracellular M. tuberculosis H37Rv bacteria were collected in 6, 24, and 48 h for culture in L-J medium. CFU is the number of colony-forming units. (c, d) THP-1 cells infected with M. tuberculosis H37Rv at MOIs of 0, 1, 5, or 10 for 24 h. IFI44L expression measured by qPCR and Western blot analysis. (e, f) THP-1 cells infected with M. tuberculosis H37Rv at an MOI of 5 for 0, 6, 12, and 24 h and IFI44L level detected by qPCR and Western blot analysis. Values are presented as levels relative to β-actin and GAPDH. , , and .

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