Increased CD4+CD8+ Double-Positive T Cell in Patients with Primary Sjögren’s Syndrome Correlated with Disease Activity
Table 1
Characteristics of study subjects.
pSS patients
Health controls
Number ()
35
35
—
Age (years)
55 (41-65)
57 (36-63)
0.71
Gender (male/female)
2/33
3/32
—
Disease duration (years)
2.50 (1.00-8.25)
—
—
Anti-SSA (+/−)
27/8
—
—
Anti-SSB (+/−)
19/16
—
—
Antinuclear antibodies (+/−)
25/10
—
—
ESSDAI score
6.00 (3.00-9.00)
—
—
SSDAI score
4.00 (2.00-5.00)
—
—
CRP (mg/L)
5.70 (4.60-8.00)
1.80 (1.50-2.20)
0.003
ESR (mm/h)
20 (11-44)
10 (6-14)
<0.001
C3 (g/L)
0.97 (0.82-1.10)
1.10 (0.94-1.21)
0.02
C4 (g/L)
0.18 (0.13-0.25)
0.23 (0.18-0.29)
0.007
IgG (g/L)
15.50 (11.60-20.90)
12.10 (11.40-12.60)
<0.001
IgA (g/L)
2.24 (1.63-3.28)
2.19 (1.49-2.55)
0.36
IgM, g/L
1.10 (0.87-1.63)
1.33 (1.04-1.95)
0.47
Immunosuppressive therapy (Y/N)
19/16
—
—
The data are expressed as the median (25% percentile-75% percentile). The Mann-Whitney test was used for comparison between pSS patients and health controls.
