Knockdown of lncRNA CCAT1 Inhibits the Progression of Colorectal Cancer via hsa-miR-4679 Mediating the Downregulation of GNG10

Figure 2

hsa-miR-4679 directly bound to lncRNA CCAT1. (a) The relative expression level of hsa-miR-7-5p, hsa-miR-1246, hsa-miR-8063, hsa-miR-6879-5p, and hsa-miR-4679 after knockdown of CCAT1. (b) The relative expression level of hsa-miR-4679 in CRC and normal tissues. (c) The strategy for the construction of luciferase reporter vectors to detect the binding between CCAT1 and hsa-miR-4679. (d) Relative luciferase activity in cotransfection of CCAT1 and hsa-miR-4679 group was significantly reduced. (e) RIP assay with anti-AGO2 antibody was performed to confirm the binding between CCAT1 and hsa-miR-4679. and .

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