Expression of Killer Immunoglobulin Receptor Genes among HIV-Infected Individuals with Non-AIDS Comorbidities
Table 8
The relationship between KIR clusters and non-AIDS associated comorbid conditions.
Diabetes
Hyperlipidemia
Hypertension
CVD
OR (95% CI)
value
OR (95% CI)
value
OR (95% CI)
value
OR (95% CI)
value
KIR clusters
Cluster 1a
2.7 (0.44-16.45)
0.283
1.27 (0.45-3.58)
0.649
1.7 (0.52-5.82)
0.373
0.8 (0.18-3.6)
0.786
Cluster 2
1.14 (0.19-6.65)
0.886
0.5 (0.16-1.4)
0.179
1.3 (0.4-4.29)
0.664
1.04 (0.25-4.31)
0.954
Cluster 3
2.4 (0.39-15.53)
0.34
1.2 (0.41-3.54)
0.715
1.6 (0.43-5.68)
0.501
0.2 (0.02-1.83)
0.154
Cluster 4
0.14 (0.01-2.04)
0.151
0.4 (0.08-2.06)
0.272
0.6 (0.1-3)
0.493
1 -
—
Cluster 5
1 -
—
0.7 (0.12-4.29)
0.721
0.08 (0.006-0.99)
0.05
0.2 (0.03-1.46)
0.113
Centromeric cluster
2.4 (0.39-15.43)
0.34
0.9 (0.29-2.63)
0.82
1.2 (0.32-4.37)
0.811
0.2 (0.02-2.13)
0.195
CVD: cardiovascular disease; OR: odds ratio; 95% CI: 95% confidence interval. aCluster 1 is the same as telomeric cluster. We adjusted for age, sex, and family history of comorbid condition. For hypertension and CVD, we also adjusted for smoking and alcohol use. We applied Bonferroni correction, and thus, values of <0.004 were considered significant.
