Research Article

An In Vitro Comparison of Costimulatory Domains in Chimeric Antigen Receptor T Cell for Breast Cancer Treatment

Figure 2

Specific lysis of CAR T cell targeting tumor associated MUC1. (a) Expression of MUC1 on different cancer cell lines, MCF-7 and CaOV3. (b) Six-hour cytotoxicity assay at E:T ratio 40 : 1, 20 : 1, 10 : 1, 5 : 1, 2.5 : 1, and 1.25 : 1. Target cells: MCF-7 (left) and CaOV3 (right). The data shown are from four donors. Significance was determined by one-way ANOVA, for , for , and for .
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