A Systematic Pan-Cancer Analysis of YY1 Aberrations and their Relationship with Clinical Outcome, Tumor Microenvironment, and Therapeutic Targets

Figure 10

Enrichment analysis of YY1 related genes. (a) Using the STRING tool, we first gathered experimentally determined YY1-binding proteins. (b) The top 100 YY1 associated genes in the TCGA project were obtained using the GEPIA2 method, and the expression association between YY1 and SP3, SMEK1, CPSF2, PPP2R5E, PAPOLA, MARCH7, and other selected target genes was analyzed. (c) Display the corresponding heat map data for detailed cancer types. (d) YY1-binding and related genes were cross-analyzed. (e) YY1 binding and interaction genes were used to create a KEGG pathway analysis. (f) YY1 binding and interaction genes were used to create a GO enrichment analysis.

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