Interleukin-32γ in the Control of Acute Experimental Chagas Disease

Figure 1

Interleukin-32γ controls parasitemia and protects mice in the acute phase of Chagas disease. WT and IL-32γTg mice were subcutaneously infected with 1,000 blood trypomastigote forms of T. cruzi Colombian strain. (a) Parasitemia was determined by counting the number of trypomastigotes in blood collected from the caudal vein. # (differences within the same group, comparing first day with detectable parasitemia vs. the time point observed) and (WT vs. IL-32γTg mice). Significant statistical differences at , two-way ANOVA with Bonferroni post hoc test. (b) Percent survival of infected IL-32γTg and WT mice, , Log-Rank test.

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