lncRNA FR215775 Regulates Th2 Differentiation in Murine Allergic Rhinitis

<div>Knockdown of lncRNA FR215775 affect Th2 cell function and differentiation; (a) the concentrations of IL-4 and IL-5 in sh-FR215775 group were significantly lower than those in the control group; (b, c) the proportion of Th2 cells decreased whereas the proportion of Th1 and Th17 cells increased in the cells of sh-FR215775 group; (d, e) the proportion of induced Th2 cells was significantly reduced in the sh-FR215775 group; (<span class="nowrap"><svg height="10.7395pt" id="M30" style="vertical-align:-0.6370001pt" version="1.1" viewbox="-0.0498162 -10.1025 50.9184 10.7395" width="50.9184pt" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink"><g transform="matrix(.0091,0,0,-0.0091,0,-5.741)"><path d="M486 158C486 177 478 202 466 220C413 228 386 236 336 262C386 288 413 297 466 304C478 323 486 347 485 366C470 376 444 381 422 380C389 338 368 319 321 288C323 345 329 372 349 422C339 442 322 461 305 470C289 461 271 442 262 422C281 372 287 345 290 288C243 319 222 338 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Journal of Immunology Research

fig3

Figure 3

Figure 3: lncRNA FR215775 Regulates Th2 Differentiation in Murine Allergic Rhinitis 