C-Reactive Protein Knockout Attenuates Temporomandibular Joint Inflammation in Rats

Figure 5

Histological changes in the synovial membrane. (a)–(d) Representative images of H&E-stained slides showing synovial membranes of the anterior superior region from Con, CFA, CRP, and groups, respectively. (e)–(h) Representative images of synovial membranes of the posterior superior region from Con, CFA, CRP, and groups, respectively. The orange box indicates a square used for counting infiltrating inflammatory cells. (i)–(l) Magnified images of areas in orange boxes from (e)–(h). (m) Inflammatory score based on inflammatory cell infiltrate (II) and thickening of the synovial membrane (TS). (n) Number of mononucleated cells in a square of the synovial membrane measured to determine inflammatory infiltration. (; ; ).

(a)

(b)

(c)

(d)

(e)

(f)

(g)

(h)

(i)

(j)

(k)

(l)

(m)

(n)