In the last decade, immunotherapies methods have been playing a key role in the clinical treatment of cancer. It has been clearly demonstrated that the characteristics of different cancers were the basement for the specific cancer immunotherapies. Cancer cell can be attacked by immune system targeting tumor-associated antigens via active immunotherapy; moreover, antitumor responses can also be enhanced by using antibodies, lymphocytes, or cytokines via passive immunotherapies. The competence of immunotherapies, however, is largely dependent on the properties of immune response in the tumor microenvironment. Therefore, a thorough understanding of above process will help us find more effective cancer immunotherapies strategies.

The high-quality original research articles as well as review articles are invited to understand and clarify the related fundamental knowledge and underlying mechanism of immune response during the respective cancer immunotherapies process so as to explore more new therapeutic strategies and improve the clinical efficiency on cancer treatment.

Potential topics include but are not limited to the following:

• Alteration of immune cell properties in cancer development
• Immunomodulation of the tumor microenvironment by immunotherapy
• Exploration of cancer immunotherapy targets
• Combining immunotherapy and targeted therapies in cancer treatment
• Pharmacological strategies for cancer immunotherapy