Journal of Immunology Research

Systemic Lupus Erythematosus


Publishing date
06 Jul 2012
Status
Published
Submission deadline
06 Jan 2012

Lead Editor

1Montefiore Medical Center, Bronx, USA; Division of Rheumatology, Albert Einstein College of Medicine, Bronx, NY 10461, USA

2Section of Rheumatology, Temple University School of Medicine, Philadelphia, PA 19140, USA

3Center for Autoimmunity and Musculoskeletal Diseases, The Feinstein Institute for Medical Research, Manhasset, NY 11030, USA

4Division of Rheumatology, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA


Systemic Lupus Erythematosus

Description

Systemic lupus erythematosus (SLE) is a systemic autoimmune disease characterized by diverse immunological abnormalities, together with clinical involvement of multiple organ systems. Over the last decade, there have been many advances in understanding the genetic and environmental contributions to the pathogenesis of SLE and the cellular and molecular basis for the loss of tolerance and generation of tissue damage. However, our increased knowledge has yet to translate into marked improvements in patient prognosis. Organ involvement, particularly of the kidney and brain, remain significant causes of morbidity and mortality in lupus patients. It is hoped that better targeted biologic therapies will contribute to improved clinical outcomes.

We invite authors to submit original basic, clinical, and translational research and review articles that contribute to the understanding of SLE, lupus-associated brain and renal involvement, and current and promising therapeutic approaches. We are interested in papers describing discoveries in genetic susceptibility, mechanisms pertaining to innate and adoptive immunity, the pathogenesis of brain, kidney, and other target organ involvement, and disease biomarkers. Papers addressing novel therapeutics, including drugs recently approved or in advanced clinical development, are welcome as well. Potential topics include, but are not limited to:

  • B cells, T cells, dendritic cells, NK cells, neutrophils, and macrophages in lupus
  • Toll-like receptors, alpha-interferon, cytokines, complement, and apoptosis in SLE
  • Loss of self-tolerance in lupus
  • SLE genetics, genomics, proteomics, and transcriptomics
  • Pathogenesis of renal disease and tissue damage in lupus
  • Gender differences in the pathogenesis and outcome of lupus nephritis
  • Ethnic considerations in treatment and prognosis of lupus nephritis
  • New spontaneous and induced models of lupus-associated organ involvement
  • Pathogenesis of neuropsychiatric SLE
  • Novel imaging techniques in CNS lupus
  • Biomarkers for early diagnosis, prognostication, and monitoring treatment
  • New biologic and nonbiologic approaches to treat organ involvement in SLE

Before submission authors should carefully read over the journal's Author Guidelines, which are located at http://www.hindawi.com/journals/jir/guidelines/. Prospective authors should submit an electronic copy of their complete manuscript through the journal Manuscript Tracking System at http://mts.hindawi.com/ according to the following timetable:


Articles

  • Special Issue
  • - Volume 2012
  • - Article ID 437282
  • - Editorial

Systemic Lupus Erythematosus

Chaim Putterman | Roberto Caricchio | ... | Harris Perlman
  • Special Issue
  • - Volume 2012
  • - Article ID 380391
  • - Review Article

Hematopoietic Stem Cell Transplantation for Systemic Lupus Erythematosus

Alberto M. Marmont du Haut Champ
  • Special Issue
  • - Volume 2012
  • - Article ID 826182
  • - Research Article

Gene Expression Profile Reveals Abnormalities of Multiple Signaling Pathways in Mesenchymal Stem Cell Derived from Patients with Systemic Lupus Erythematosus

Yu Tang | Xiaolei Ma | ... | Lingyun Sun
  • Special Issue
  • - Volume 2012
  • - Article ID 273291
  • - Clinical Study

Double Allogenic Mesenchymal Stem Cells Transplantations Could Not Enhance Therapeutic Effect Compared with Single Transplantation in Systemic Lupus Erythematosus

Dandan Wang | Kentaro Akiyama | ... | Lingyun Sun
  • Special Issue
  • - Volume 2012
  • - Article ID 370516
  • - Review Article

Epstein-Barr Virus and Systemic Lupus Erythematosus

Anette Holck Draborg | Karen Duus | Gunnar Houen
  • Special Issue
  • - Volume 2012
  • - Article ID 967584
  • - Clinical Study

Association of Intrarenal B-Cell Infiltrates with Clinical Outcome in Lupus Nephritis: A Study of 192 Cases

Yan Shen | Chuan-Yin Sun | ... | Cheng-De Yang
  • Special Issue
  • - Volume 2012
  • - Article ID 584374
  • - Review Article

Role of MHC-Linked Susceptibility Genes in the Pathogenesis of Human and Murine Lupus

Manfred Relle | Andreas Schwarting
  • Special Issue
  • - Volume 2012
  • - Article ID 568564
  • - Research Article

Systemic-Lupus-Erythematosus-Related Acute Pancreatitis: A Cohort from South China

Yanlong Yang | Yujin Ye | ... | Hanshi Xu
  • Special Issue
  • - Volume 2012
  • - Article ID 823085
  • - Review Article

Balance between Regulatory T and Th17 Cells in Systemic Lupus Erythematosus: The Old and the New

Alessia Alunno | Elena Bartoloni | ... | Roberto Gerli
  • Special Issue
  • - Volume 2012
  • - Article ID 139365
  • - Review Article

Autoantibodies and Resident Renal Cells in the Pathogenesis of Lupus Nephritis: Getting to Know the Unknown

Susan Yung | Tak Mao Chan
Journal of Immunology Research
 Journal metrics
Acceptance rate45%
Submission to final decision61 days
Acceptance to publication37 days
CiteScore5.100
Impact Factor3.327
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