Journal of Immunology Research

Human Monoclonal Antibodies as a New Class of Antiinfective Compounds


Publishing date
02 Aug 2013
Status
Published
Submission deadline
15 May 2013

Lead Editor

1Medical School, Universitá Vita-Salute San Raffaele, Milan, Italy

2GeNeuro SA, 1228 Geneva, Switzerland

3Oklahoma Medical Research Foundation, Oklahoma City, OK 73104, USA


Human Monoclonal Antibodies as a New Class of Antiinfective Compounds

Description

Over the last thirty years, monoclonal antibodies (mAb) have made a dramatic transformation from useful scientific tools to extremely powerful human therapeutics. At this moment, more than 30 mAbs are available in the market for very diverse indications, with sales worldwide totaling more than 30 billions of dollars in 2010. While polyclonal antibody preparations, usually known as antisera, represent an historic treatment dating back over 200 years, to date, there is only one antiinfectious disease mAb approved for clinical use, although there are several mAbs deep in the clinical pipeline. Thus, it is likely that, after anticancer and anti-inflammatory therapy, the field of infectious disease will be the next arena where human mAbs will become important players. We are interested in articles that explore the utilization of human mAbs for the prevention and treatment of infectious diseases. Potential topics include, but are not limited to:

  • Clinical utilization of existing antiinfective human mAbs
  • Development of novel antiinfective human mAbs to address unmet clinical needs
  • Discovery and development of antiviral mAbs
  • Discovery and development of antibacterial and antitoxin mAbs
  • Discovery and development of antifungal mAbs
  • mAbs as a tool for dissecting human antibody responses and the design of novel vaccines

Before submission authors should carefully read over the journal's Author Guidelines, which are located at http://www.hindawi.com/journals/jir/guidelines/. Prospective authors should submit an electronic copy of their complete manuscript through the journal Manuscript Tracking System at http://mts.hindawi.com/submit/journals/jir/hma/ according to the following timetable:


Articles

  • Special Issue
  • - Volume 2013
  • - Article ID 297120
  • - Editorial

Human Monoclonal Antibodies as a New Class of Antiinfective Compounds

Roberto Burioni | Alois B. Lang | J. Donald Capra
  • Special Issue
  • - Volume 2013
  • - Article ID 716961
  • - Research Article

A Simple Methodology for Conversion of Mouse Monoclonal Antibody to Human-Mouse Chimeric Form

Vinh T. Dang | Kedar D. Mandakhalikar | ... | Yee-Joo Tan
  • Special Issue
  • - Volume 2013
  • - Article ID 450963
  • - Review Article

Structural and Antigenic Definition of Hepatitis C Virus E2 Glycoprotein Epitopes Targeted by Monoclonal Antibodies

Giuseppe Sautto | Alexander W. Tarr | ... | Massimo Clementi
  • Special Issue
  • - Volume 2013
  • - Article ID 403121
  • - Review Article

Human Monoclonal Antibody-Based Therapy in the Treatment of Invasive Candidiasis

Francesca Bugli | Margherita Cacaci | ... | Francesco Paroni Sterbini
  • Special Issue
  • - Volume 2013
  • - Article ID 521231
  • - Review Article

Peptide-Based Vaccinology: Experimental and Computational Approaches to Target Hypervariable Viruses through the Fine Characterization of Protective Epitopes Recognized by Monoclonal Antibodies and the Identification of T-Cell-Activating Peptides

Matteo Castelli | Francesca Cappelletti | ... | Nicola Clementi
  • Special Issue
  • - Volume 2013
  • - Article ID 967581
  • - Review Article

JC Polyomavirus (JCV) and Monoclonal Antibodies: Friends or Potential Foes?

Roberta Antonia Diotti | Akira Nakanishi | ... | Massimo Clementi
  • Special Issue
  • - Volume 2013
  • - Article ID 801581
  • - Research Article

Increased Risk of RSV Infection in Children with Down's Syndrome: Clinical Implementation of Prophylaxis in the European Union

Dianne van Beek | Bosco Paes | Louis Bont
  • Special Issue
  • - Volume 2013
  • - Article ID 917068
  • - Research Article

Respiratory-Related Hospitalizations following Prophylaxis in the Canadian Registry for Palivizumab (2005–2012) Compared to Other International Registries

Bosco Paes | Ian Mitchell | ... | Krista L. Lanctôt
  • Special Issue
  • - Volume 2013
  • - Article ID 359683
  • - Review Article

The Use of Humanized Monoclonal Antibodies for the Prevention of Respiratory Syncytial Virus Infection

Marcello Lanari | Silvia Vandini | ... | Giacomo Faldella
  • Special Issue
  • - Volume 2013
  • - Article ID 632893
  • - Review Article

Multiantibody Strategies for HIV

Andrew Hiatt | Larry Zeitlin | Kevin J. Whaley
Journal of Immunology Research
 Journal metrics
Acceptance rate40%
Submission to final decision91 days
Acceptance to publication32 days
CiteScore3.330
Impact Factor3.404
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