Journal of Immunology Research

Autoimmunity in Reproductive Health and Pregnancy


Status
Published

1Medical Faculty of University of Rzeszow, Rzeszow, Poland

2Vetha Center for Transdisciplinary Studies, Newark, USA

3University of Antwerp, Antwerp, Belgium


Autoimmunity in Reproductive Health and Pregnancy

Description

The immune system plays an important role in the development and success of pregnancy. Physiologically, the maternal immune system should host “non-self” antigens expressed by the embryo. Moreover, autoimmune disorders, autoantibodies, and lymphocyte subpopulations can affect pregnancy progress and can lead to maternal complications, sometimes life-threatening. In this context, it is well known that antiphospholipid antibodies are related to a wide spectrum of obstetric complications, ranging from eclampsia to recurrent miscarriages. In addition, natural killer subpopulations influence pregnancy outcome. It has been suggested that a good immunological state favours embryo implantation. A growing body of evidences also relate sterility and infertility to autoimmune disorders.

On the other hand, pregnancy on its turn may represents a risk condition for the development and worsening of autoimmunity, since hormonal and antigenic stimuli may cause a shift in the immune balance.

We invite investigators to contribute original research articles as well as clinical studies that seek to address the role of autoimmune diseases, autoantibodies, and immune cells in the pathogenesis of obstetric pathologies and sterility/infertility. A particular interest will be given to exploring and discussing targeted and integrative (holistic) treatment of autoimmunity during pregnancy.

Potential topics include but are not limited to the following:

  • Autoantibodies related to pregnancy disorders
  • Lymphocyte subpopulations and recurrent miscarriages
  • Infertility/sterility and autoimmunity
  • Hormonal balance and autoimmunity
  • Drugs, autoimmunity, and pregnancy
  • Integrative treatment of autoimmunity related to pregnancy and infertility/sterility

Articles

  • Special Issue
  • - Volume 2018
  • - Article ID 9501865
  • - Editorial

Autoimmunity in Reproductive Health and Pregnancy

Jacek Tabarkiewicz | Senthamil R. Selvan | Nathalie Cools
  • Special Issue
  • - Volume 2017
  • - Article ID 4570715
  • - Research Article

Elevated Serum Level of HMGB1 in Patients with the Antiphospholipid Syndrome

Valeria Manganelli | Antonella Capozzi | ... | Roberta Misasi
  • Special Issue
  • - Volume 2017
  • - Article ID 2810202
  • - Research Article

Hydroxychloroquine Use in Lupus Patients during Pregnancy Is Associated with Longer Pregnancy Duration in Preterm Births

S. J. Kroese | M. J. H. de Hair | ... | R. D. E. Fritsch-Stork
  • Special Issue
  • - Volume 2017
  • - Article ID 3175394
  • - Research Article

Fas-Related Apoptosis of Peritoneal Fluid Macrophages in Endometriosis Patients: Understanding the Disease

Marek Gogacz | Krzysztof Gałczyński | ... | Jan Kotarski
  • Special Issue
  • - Volume 2017
  • - Article ID 4809294
  • - Research Article

An Exploration of the Impact of Anticentromere Antibody on Early-Stage Embryo

Ying Ying | Xi Guo | ... | Canquan Zhou
  • Special Issue
  • - Volume 2017
  • - Article ID 8245879
  • - Research Article

Maternal and Perinatal Outcome in Women with Systemic Lupus Erythematosus: A Retrospective Bicenter Cohort Study

Sylvia J. Kroese | Carolien N. H. Abheiden | ... | Ruth D. E. Fritsch-Stork
  • Special Issue
  • - Volume 2017
  • - Article ID 8596181
  • - Clinical Study

Impacts of Anti-dsDNA Antibody on In Vitro Fertilization-Embryo Transfer and Frozen-Thawed Embryo Transfer

Jiao Fan | Yiping Zhong | Cuina Chen
Journal of Immunology Research
 Journal metrics
Acceptance rate45%
Submission to final decision61 days
Acceptance to publication37 days
CiteScore5.100
Impact Factor3.327
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