Journal of Immunology Research

Inflammation in Cancer: Part of the Problem or Part of the Solution?


Status
Published

Lead Editor

1“Victor Babes” National Institute of Pathology, Bucharest, Romania

2University of Verona, Verona, Italy

3University of Pittsburgh, Pittsburgh, USA


Inflammation in Cancer: Part of the Problem or Part of the Solution?

Description

Although a process was described 2000 years ago first by Celsus and then by Galen, inflammation and its precise role in disease still are a subject of intense research. The immune system triggers an array of inflammatory reactions as a response to any exogenous and/or endogenous homeostasis disturbing factors. These processes are vital to preserve cells, tissues, and organ integrity, but as they comprise complex elements, regulation of this array of events is the main key for maintaining a normal physiological, efficient process. The regulatory mechanisms, some of them still unknown, need to balance the immune response. Thus, an insufficient response may cause immunodeficiency resulting in infection, cancer, and neurodegeneration.

As inflammation can be classified as either acute or chronic, these facets of the process can follow tumorigenesis. In the present special issue we intend to gather works that tackle these issues, namely, chronic inflammation that triggers/favours oncogenesis of solid tumors, on one hand. On the other hand, we intend to gather works that show the inflammation process as mechanism of efficient immune therapy in oncology.

We invite investigators to contribute to reviews and original papers describing recent findings in oncology field with focus on inflammation as part of the problem or part of the solution in tumor process/disease evolution.

Potential topics include but are not limited to the following:

  • Proteomics/immunoproteomics biomarkers for monitoring inflammation in skin cancer, brain cancer, and other types of tumors
  • The innate-adaptive immune systems interface in inflammation
  • Signaling inflammation-mediated events as tumorigenesis triggers
  • Inflammasomes in cancer
  • Inflammation and transcriptomics
  • New methodological approaches for inflammation evaluation in cancer
  • New avenues of immune-therapy in cancer
  • Personalized medicine through inflammatory status evaluation
  • Bioinformatics: main tool for human inflammasome approaches
  • Inflammaging as tumorigenesis trigger

Articles

  • Special Issue
  • - Volume 2018
  • - Article ID 7169081
  • - Review Article

On the Dual Role of Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1 (CEACAM1) in Human Malignancies

Andreea Calinescu | Gabriela Turcu | ... | Ioana A. Badarau
  • Special Issue
  • - Volume 2018
  • - Article ID 4735752
  • - Research Article

Activation of PAR4 Upregulates p16 through Inhibition of DNMT1 and HDAC2 Expression via MAPK Signals in Esophageal Squamous Cell Carcinoma Cells

Ming Wang | Shuhong An | ... | Zhaojin Wang
  • Special Issue
  • - Volume 2018
  • - Article ID 9349207
  • - Research Article

Inflammatory-Driven Angiogenesis in Bone Augmentation with Bovine Hydroxyapatite, B-Tricalcium Phosphate, and Bioglasses: A Comparative Study

Vlad M. Anghelescu | Ioana Neculae | ... | Alexandru Bucur
  • Special Issue
  • - Volume 2018
  • - Article ID 2180373
  • - Review Article

Inflammation-Related Mechanisms in Chronic Kidney Disease Prediction, Progression, and Outcome

Simona Mihai | Elena Codrici | ... | Cristiana Tanase
  • Special Issue
  • - Volume 2018
  • - Article ID 2498576
  • - Research Article

Caveolin-1-Knockout Mouse as a Model of Inflammatory Diseases

Elena Codrici | Lucian Albulescu | ... | Mihail E. Hinescu
  • Special Issue
  • - Volume 2018
  • - Article ID 5315816
  • - Review Article

New Insights in the Pathogenesis of HPV Infection and the Associated Carcinogenic Processes: The Role of Chronic Inflammation and Oxidative Stress

Simona Roxana Georgescu | Cristina Iulia Mitran | ... | Mircea Tampa
Journal of Immunology Research
 Journal metrics
Acceptance rate45%
Submission to final decision61 days
Acceptance to publication37 days
CiteScore5.100
Impact Factor3.327
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