Journal of Immunology Research

Immune and Inflammatory-Mediated Disorders: From Bench to Bedside


Publishing date
01 May 2018
Status
Published
Submission deadline
05 Jan 2018

Lead Editor

1University of G. D’Annunzio, Chieti, Italy

2Istituto Superiore di Sanità, Rome, Italy

3University of Miami, Coral Gables, USA


Immune and Inflammatory-Mediated Disorders: From Bench to Bedside

Description

The immune system consists of many biological structures (molecules and cells) that act in a coordinated manner to protect the organism against disease and are distributed in every tissue of the body. Inflammation is the central driving force in diseases affecting nearly all organs and systems of the body including skin, gut, lungs, brain, and cardiovascular system and the mononuclear phagocyte lineage plays a pivotal role in innate immunity. Age- and gender-related differences in immune response contribute to increasing the complexity in the diagnosis, treatment, and prevention of the immune- and inflammatory-mediated disorders.

Major scientific progresses result from the interface of high-throughput technologies for immunological research, cellular and animal models, pharmacology, and clinical practice.

The aim of this special issue is to highlight the achievements obtained in the basic, translational, and clinical immunology. We invite authors to submit high-quality original research and review articles addressing the role of monocytes/macrophages and their tissue-differentiated derivatives, as well as immune mediators in inflammatory and immune-mediated diseases. In particular, the issue will focus on the effects of aging, gender, and gut microbiota in the development of those disorders. New therapeutic strategies will be also included in the issue.

Potential topics include but are not limited to the following:

  • Cellular and molecular mechanisms underlying inflammatory- and immune-mediated disorders
    • Crosstalk between cells of innate immunity
    • Cytokines/chemokines and receptor activation
    • Epigenetic modifications
  • Environmental and life style influences on inflammatory- and immune-mediated disorders
    • Aging
    • Gender
    • Gut microbiota
    • Obesity and metabolic syndrome
  • Translating immunology
    • Interplay between inflammation and chronic/degenerative diseases
    • Advances and future insights in therapeutic interventions

Articles

  • Special Issue
  • - Volume 2018
  • - Article ID 7197931
  • - Editorial

Immune and Inflammatory-Mediated Disorders: From Bench to Bedside

Marcella Reale | Lucia Conti | Diana Velluto
  • Special Issue
  • - Volume 2018
  • - Article ID 2361963
  • - Review Article

The Immunologic Role of Gut Microbiota in Patients with Chronic HBV Infection

Ruilin Yang | Yao Xu | ... | Huichao Wang
  • Special Issue
  • - Volume 2018
  • - Article ID 6249085
  • - Research Article

TRIF Regulates BIC/miR-155 via the ERK Signaling Pathway to Control the ox-LDL-Induced Macrophage Inflammatory Response

Yaxi Wu | Jinshan Ye | ... | Lixia Yang
  • Special Issue
  • - Volume 2018
  • - Article ID 7213760
  • - Review Article

Modulation of Immune-Inflammatory Responses in Abdominal Aortic Aneurysm: Emerging Molecular Targets

Hanrong Li | Shuling Bai | ... | Jun Fan
  • Special Issue
  • - Volume 2018
  • - Article ID 2724951
  • - Review Article

Microbiota Composition and the Integration of Exogenous and Endogenous Signals in Reactive Nasal Inflammation

Francesco Antonio Salzano | Luigi Marino | ... | Vincenzo Casolaro
  • Special Issue
  • - Volume 2018
  • - Article ID 5389282
  • - Research Article

NMO-IgG and AQP4 Peptide Can Induce Aggravation of EAMG and Immune-Mediated Muscle Weakness

Tehila Mizrachi | Livnat Brill | ... | Adi Vaknin-Dembinsky
  • Special Issue
  • - Volume 2018
  • - Article ID 3256908
  • - Research Article

Downregulation of iNOS, IL-1β, and P2X7 Expression in Mast Cells via Activation of PAR4 Contributes to the Inhibition of Visceral Hyperalgesia in Rats

Yanli Hao | Hao Niu | ... | Zhaojin Wang
  • Special Issue
  • - Volume 2018
  • - Article ID 4874193
  • - Research Article

The Relationship between a New Biomarker of Vagal Neuroimmunomodulation and Survival in Two Fatal Cancers

Y. Gidron | M. De Couck | ... | R. Maréchal
  • Special Issue
  • - Volume 2018
  • - Article ID 5301548
  • - Review Article

Roles of Host Immunity in Viral Myocarditis and Dilated Cardiomyopathy

Lifang Zhao | Zhaoying Fu
  • Special Issue
  • - Volume 2018
  • - Article ID 1060421
  • - Research Article

How to Distinguish Patients with pSS among Individuals with Dryness without Invasive Diagnostic Studies

Agata Sebastian | Maciej Sebastian | ... | Piotr Wiland
Journal of Immunology Research
 Journal metrics
Acceptance rate40%
Submission to final decision65 days
Acceptance to publication30 days
CiteScore3.330
Impact Factor3.404
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