Journal of Immunology Research

Roles of Infiltrating Immune Cells in Cancer


Publishing date
01 Jan 2023
Status
Published
Submission deadline
02 Sep 2022

Lead Editor

1Fudan University, Shanghai, China

2Harvard University, Cambridge, USA

3Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China


Roles of Infiltrating Immune Cells in Cancer

Description

Tumor micro-environment (TME) encompasses a wide range of complex interactions between tumor stroma, tumor cells, and immune cells. The infiltration of cancer cells by immune cells is receiving widespread attention as cancer progression is shaped by the dynamic equilibrium between cancer cells and infiltrating immune cells. Although our understanding of the roles of immune cells in cancer proliferation, invasion, and treatment continues to progress, there are many unknowns in this field. Recent techniques such as single-cell sequencing as well as several computational methods have provided new insights into the composition of infiltrating immune cells. As a result, there is an emerging interest to advance understanding of the roles of infiltrating immune cells in cancer.

This Special Issue aims to investigate the composition and functions of infiltrating immune cells in solid tumors. We aim to highlight the subsets of infiltrating immune cells which play critical roles in the development of cancers. We invite submissions exploring the molecular mechanisms of how tumor cells might be influenced by infiltrating immune cells either by direct contact or by secreting cytokines. We also invite research focusing on the alterations of infiltrating immune cells in immunotherapy, radiotherapy, and chemotherapy, and their effects on treatment outcome. We hope this Special Issue can provide a multi-perspective view of infiltrating immune cells and bring new insights to improve the prognosis of cancer patients. We welcome both original research and review papers.

Potential topics include but are not limited to the following:

  • Composition of infiltrating immune cells
  • Special subsets of infiltrating immune cells
  • Effects of infiltrating immune cells on cancer cells
  • Effects of infiltrating immune cells on other immune cells or microenvironment
  • Roles of infiltrating immune cells in cancer proliferation, invasion, and metastasis
  • Roles of infiltrating immune cells in tumor escape from immunosurveillance
  • Roles of infiltrating immune cells in immunotherapy
  • Roles of infiltrating immune cells in radiotherapy, chemotherapy, or other treatment
  • Effects of cancer cells on infiltrating immune cells
  • Potential targets of immunotherapy

Articles

  • Special Issue
  • - Volume 2023
  • - Article ID 9946911
  • - Research Article

Circadian Regulator-Mediated Molecular Subtypes Depict the Features of Tumor Microenvironment and Indicate Prognosis in Head and Neck Squamous Cell Carcinoma

Ling Aye | Zhanying Wang | ... | Dehui Wang
  • Special Issue
  • - Volume 2023
  • - Article ID 4987832
  • - Research Article

Characterization of Infiltrating Immune Cells and Secretory or Membrane-Associated Proteins in KRAS Lung Adenocarcinoma

Yunyi Bian | Guoshu Bi | ... | Hong Fan
  • Special Issue
  • - Volume 2022
  • - Article ID 3205040
  • - Research Article

Downregulated PRNP Facilitates Cell Proliferation and Invasion and Has Effect on the Immune Regulation in Ovarian Cancer

Kuan Hu | Xiaofang Zhang | ... | Juanni Li
  • Special Issue
  • - Volume 2022
  • - Article ID 9589895
  • - Research Article

Expression Analysis of Ligand-Receptor Pairs Identifies Cell-to-Cell Crosstalk between Macrophages and Tumor Cells in Lung Adenocarcinoma

Xiaodong Yang | Zhao An | ... | Yuming Zhu
  • Special Issue
  • - Volume 2022
  • - Article ID 5209607
  • - Research Article

Identification of a Hypoxia-Angiogenesis lncRNA Signature Participating in Immunosuppression in Gastric Cancer

Zicheng Wang | Xisong Liang | ... | Quan Cheng
  • Special Issue
  • - Volume 2022
  • - Article ID 4355890
  • - Research Article

Pan-Cancer Analysis of B4GALNT1 as a Potential Prognostic and Immunological Biomarker

Hang Yi | Yiwen Lin | ... | Yousheng Mao
  • Special Issue
  • - Volume 2022
  • - Article ID 6555810
  • - Research Article

A Novel Prognostic Signature Revealed the Interaction of Immune Cells in Tumor Microenvironment Based on Single-Cell RNA Sequencing for Lung Adenocarcinoma

Xing Jin | Zhengyang Hu | ... | Yu Shi
  • Special Issue
  • - Volume 2022
  • - Article ID 9140461
  • - Research Article

Downregulated Copper Homeostasis-Related Gene FOXO1 as a Novel Indicator for the Prognosis and Immune Response of Breast Cancer

Rong Zeng | Bi Peng | Emin Peng
  • Special Issue
  • - Volume 2022
  • - Article ID 6521290
  • - Research Article

Novel Circulating Tumour Cell-Related Risk Model Indicates Prognosis and Immune Infiltration in Lung Adenocarcinoma

Lu Liang | Yueying Liu | ... | Yiqun Jiang
  • Special Issue
  • - Volume 2022
  • - Article ID 9089397
  • - Research Article

Identification of Significant Secreted or Membrane-Located Proteins in Laryngeal Squamous Cell Carcinoma

Li Yan | Chunyan Hu | ... | Xiaoshen Wang
Journal of Immunology Research
 Journal metrics
See full report
Acceptance rate12%
Submission to final decision122 days
Acceptance to publication24 days
CiteScore6.000
Journal Citation Indicator0.560
Impact Factor4.1
 Submit Evaluate your manuscript with the free Manuscript Language Checker

We have begun to integrate the 200+ Hindawi journals into Wiley’s journal portfolio. You can find out more about how this benefits our journal communities on our FAQ.