Journal of Immunology Research

Immunopathogenesis of Neglected Tropical Diseases


Publishing date
01 Aug 2021
Status
Closed
Submission deadline
26 Mar 2021

1São Paulo State University, São Vicente, Brazil

2São Paulo University, São Paulo, Brazil

3Universidade Nova de Lisboa, Lisbon, Portugal

This issue is now closed for submissions.
More articles will be published in the near future.

Immunopathogenesis of Neglected Tropical Diseases

This issue is now closed for submissions.
More articles will be published in the near future.

Description

Neglected tropical diseases (NTDs) represent a set of communicable diseases affecting around one billion people worldwide, living mainly in low-income countries. Additionally, people living in close contact with vectors of infectious diseases, including wild and domestic animals, and without sanitation are the ones most affected. Thus, populations in contact with pathogens can develop different NTDs, such as leishmaniasis, Chagas disease, sleeping sickness, schistosomiasis, chromoblastomycosis, dengue fever, and onchocerciasis, among others.

Although the biological cycle of NTDs etiological agents are well-known, there is little accumulated information about the interaction between the infectious agents and innate as well as acquired immunity in the majority of NTDs. This type of data is important because it is the basis of understanding how morphophysiological changes take place in the host, and is also key to designing prophylactic strategies, such as vaccines and adjuvants as well as effective therapeutic interventions, diagnostic tests, and clinical management.

This Special Issue therefore aims to highlight the latest advances in the interactions between infectious agents that cause NTDs and the genetic and immunological background of the host, with a special focus on the role of innate and acquired immune responses using in vitro and in vivo approaches. Studies with a central focus on the immunopathology of NTDs are welcome, as is the case of immunoprophylaxis, adjuvant development, histopathology, advances in diagnosis, and new therapeutic strategies. We also welcome review articles as well as original research.

Potential topics include but are not limited to the following:

  • Infections caused by infectious agents of NTDs
  • Microbe and host cell relationship
  • Role of innate and acquired immune cells in NTDs
  • Participation of mediators of inflammation in NTDs
  • Role of host and infectious agent proteins and how they can modulate inflammatory responses
  • Histopathology and immunopathology
  • Vaccine development
  • Therapeutic strategies directed to NTDs
  • Immunomodulatory drugs and administration to NTDs
  • Advances in immunological, parasitological, and molecular diagnosis of NTDs

Articles

  • Special Issue
  • - Volume 2021
  • - Article ID 6654617
  • - Research Article

Increased TNF-α Initiates Cytoplasmic Vacuolization in Whole Blood Coculture with Dengue Virus

Rahmat Dani Satria | Tzu-Wen Huang | ... | Chiou-Feng Lin
  • Special Issue
  • - Volume 2021
  • - Article ID 6614475
  • - Review Article

Pleiotropic Effect of Hormone Insulin-Like Growth Factor-I in Immune Response and Pathogenesis in Leishmaniases

Luiza C. Reis | Eduardo Milton Ramos-Sanchez | ... | Hiro Goto
  • Special Issue
  • - Volume 2021
  • - Article ID 5568077
  • - Research Article

Improved Performance of ELISA and Immunochromatographic Tests Using a New Chimeric A2-Based Protein for Human Visceral Leishmaniasis Diagnosis

Maria Marta Figueiredo | Anna R. R. dos Santos | ... | Ana Paula Fernandes
  • Special Issue
  • - Volume 2021
  • - Article ID 6673722
  • - Research Article

Invariant Natural Killer T Cells as Key Players in Host Resistance against Paracoccidioides brasiliensis

Joes Nogueira-Neto | Flavio V. Loures | ... | Alexandre C. Keller
  • Special Issue
  • - Volume 2021
  • - Article ID 5596876
  • - Research Article

Macrophage Polarization in the Skin Lesion Caused by Neotropical Species of Leishmania sp

Carmen M. Sandoval Pacheco | Gabriela V. Araujo Flores | ... | Marcia D. Laurenti
  • Special Issue
  • - Volume 2021
  • - Article ID 6624246
  • - Research Article

Effect of Prophylactic Vaccination with the Membrane-Bound Acid Phosphatase Gene of Leishmania mexicana in the Murine Model of Localized Cutaneous Leishmaniasis

María Angélica Burgos-Reyes | Lidia Baylón-Pacheco | ... | José Luis Rosales-Encina
  • Special Issue
  • - Volume 2021
  • - Article ID 6668739
  • - Review Article

Biomarkers and Their Possible Functions in the Intestinal Microenvironment of Chagasic Megacolon: An Overview of the (Neuro)inflammatory Process

José Rodrigues do Carmo Neto | Yarlla Loyane Lira Braga | ... | Marcos Vinícius da Silva
  • Special Issue
  • - Volume 2021
  • - Article ID 6680913
  • - Research Article

Antiviral Efficacy of the Anesthetic Propofol against Dengue Virus Infection and Cellular Inflammation

Ting-Jing Shen | Chia-Ling Chen | ... | Chiou-Feng Lin
  • Special Issue
  • - Volume 2021
  • - Article ID 8828750
  • - Research Article

Nanoemulsified Butenafine for Enhanced Performance against Experimental Cutaneous Leishmaniasis

Adriana Bezerra-Souza | Jéssica A. Jesus | ... | Luiz Felipe D. Passero
  • Special Issue
  • - Volume 2021
  • - Article ID 6657785
  • - Research Article

Dual Role of Insulin-Like Growth Factor (IGF)-I in American Tegumentary Leishmaniasis

Carolina de O Mendes-Aguiar | Camilla Lopes-Siqueira | ... | Hiro Goto
Journal of Immunology Research
 Journal metrics
Acceptance rate45%
Submission to final decision61 days
Acceptance to publication37 days
CiteScore5.600
Impact Factor4.818
 Submit

Article of the Year Award: Outstanding research contributions of 2020, as selected by our Chief Editors. Read the winning articles.