Journal of Immunology Research

Tissue-Specific Immunity in Homeostasis and Diseases


Publishing date
01 Aug 2019
Status
Published
Submission deadline
22 Mar 2019

Lead Editor

1Huazhong University of Science and Technology, Wuhan, China

2The Third Affiliated Hospital of Southern Medical University, Guangzhou, China

3Houston Methodist Research Institute, Houston, USA

4Australian National University, Canberra, Australia


Tissue-Specific Immunity in Homeostasis and Diseases

Description

Unlike immune responses in primary and secondary lymphoid organs, such as thymus, bone marrow, spleen, and lymph nodes, tissue-specific immunity, including tissues of skin, liver, lung, adipose tissue, kidney, joint, and gastrointestinal tract, as well as tumors, is poorly investigated. Diversified innate and adaptive immune cells indeed reside in specific tissues, regulating homeostasis and function. Recent studies demonstrate genetic and functional distinctions between tissue-resident immune cells and their counterparts from lymphoid organs. Tissue-specialized immune cells interplay with their local environment, by direct cell-cell interaction or indirectly through cytokines and interleukins. Proper tissue-resident immunity is critical for tissue environment homeostasis, regeneration, and repair, as well as immune surveillance to pathogens. Therefore, better understanding of tissue-specific immunity would extend our knowledge and improve therapeutic strategies in wound healing, autoimmune diseases, inflammatory diseases, and infectious diseases.

This special issue aims to present recent progress in tissue-specific immunity, including both steady-state and pathological scenarios and their related clinical applications. We encourage authors to submit their original research articles, reviews, and minireviews.

Potential topics include but are not limited to the following:

  • Immune responses in nonlymphoid tissues, including liver, skin, lung, kidney, adipose tissue, joint, gastrointestinal tract, and mucosal barrier
  • Tissue-specific immune cells in the maintenance of tissue homeostasis
  • Tissue-specific immune cells in infectious and noninfectious diseases
  • Tissue-specific immune cells in autoimmune diseases
  • Tumor infiltrated immune cells
  • Immune control in tissue regeneration and repair after damage
  • Treatments targeting tissue-specific immunity

Articles

  • Special Issue
  • - Volume 2019
  • - Article ID 7616509
  • - Editorial

Tissue-Specific Immunity in Homeostasis and Diseases

Ning Wu | Erwei Sun | ... | Di Yu
  • Special Issue
  • - Volume 2019
  • - Article ID 7597382
  • - Research Article

Infiltration of Blood-Derived Macrophages Contributes to the Development of Diabetic Neuropathy

Jing-Jing Sun | Lin Tang | ... | Hui Li
  • Special Issue
  • - Volume 2019
  • - Article ID 1394191
  • - Review Article

Human Lung Microbiome on the Way to Cancer

Olga V. Kovaleva | Daniil Romashin | ... | Alexei Gratchev
  • Special Issue
  • - Volume 2019
  • - Article ID 4080735
  • - Research Article

Similar Transition Processes in Synovial Fibroblasts from Rheumatoid Arthritis and Osteoarthritis: A Single-Cell Study

Shaozhe Cai | Bingxia Ming | ... | Lingli Dong
  • Special Issue
  • - Volume 2019
  • - Article ID 9716758
  • - Research Article

Effect of TNF-α-Induced Sclerostin on Osteocytes during Orthodontic Tooth Movement

Fumitoshi Ohori | Hideki Kitaura | ... | Itaru Mizoguchi
  • Special Issue
  • - Volume 2019
  • - Article ID 9406146
  • - Research Article

STAT3 Genotypic Variant rs744166 and Increased Tyrosine Phosphorylation of STAT3 in IL-23 Responsive Innate Lymphoid Cells during Pathogenesis of Crohn’s Disease

Ying Tang | Sanda A. Tan | ... | Sarah C. Glover
  • Special Issue
  • - Volume 2019
  • - Article ID 7143241
  • - Research Article

Decreased Expression of CD14 in MSU-Mediated Inflammation May Be Associated with Spontaneous Remission of Acute Gout

Lihua Duan | Jiao Luo | ... | Jie Chen
  • Special Issue
  • - Volume 2019
  • - Article ID 3128010
  • - Research Article

Exhausted and Senescent T Cells at the Maternal-Fetal Interface in Preterm and Term Labor

Rebecca Slutsky | Roberto Romero | ... | Nardhy Gomez-Lopez
  • Special Issue
  • - Volume 2019
  • - Article ID 4813795
  • - Review Article

Sjogren’s Syndrome and TAM Receptors: A Possible Contribution to Disease Onset

Richard Witas | Ammon B. Peck | ... | Cuong Q. Nguyen
  • Special Issue
  • - Volume 2019
  • - Article ID 3658215
  • - Research Article

Soluble Markers of Antibody Secreting Cell Function as Predictors of Infection Risk in Rheumatoid Arthritis

Maria J. Gutierrez | Stephen V. Desiderio | ... | Clifton O. Bingham
Journal of Immunology Research
 Journal metrics
Acceptance rate40%
Submission to final decision60 days
Acceptance to publication36 days
CiteScore5.100
Impact Factor3.327
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