Research Article
Drug Coated Balloon-Only Strategy in De Novo Lesions of Large Coronary Vessels
Table 2
Lesion characteristics, procedural data, and device characteristics.
| | | Before PS matching | After PS matching | | Variable | de novo | ≤ 2.75 mm | >2.75 mm | p-value | ≤ 2.75 mm | >2.75 mm | p-value |
| | Number of lesions | 731 | 577 | 154 | - | 119 | 126 | - |
| | Target vessel | | | | | | | | | LAD | 299 (40.9%) | 233 (40.4%) | 66 (42.9%) | 0.025 | 44 (37.0%) | 53 (42.1%) | 0.373 | | CX | 252 (34.5%) | 212 (36.7%) | 40 (26.0%) | 46 (38.7%) | 34 (27.0%) | | RCA | 155 (21.2%) | 114 (19.8%) | 41 (26.6%) | 24 (20.2%) | 32 (25.4%) | | graft | 8 (1.1%) | 4 (0.7%) | 4 (2.6%) | 2 (1.7%) | 4 (3.2%) | | unknown | 17 (2.3%) | 14 (2.4%) | 3 (1.9%) | 3 (2.5%) | 3 (2.4%) |
| | Total occlusion | 56 (7.7%) | 47 (8.1%) | 9 (5.8%) | 0.340 | 9 (7.6%) | 7 (5.6%) | 0.525 |
| | Chronic total occlusion | 23 (3.1%) | 20 (3.5%) | 3 (1.9%) | 0.338 | 7 (5.9%) | 3 (2.4%) | 0.166 |
| | Thrombus burden | 21 (2.9%) | 14 (2.4%) | 7 (4.5%) | 0.162 | 4 (3.4%) | 4 (3.2%) | 0.934 |
| | Diffuse vessel disease | 330 (45.1%) | 270 (46.8%) | 60 (39.0%) | 0.083 | 51 (42.9%) | 52 (41.3%) | 0.801 |
| | Calcification | 144 (19.7%) | 111 (19.2%) | 33 (21.4%) | 0.544 | 21 (17.6%) | 30 (23.8%) | 0.235 |
| | Vein graft | 7 (1.0%) | 3 (0.5%) | 4 (2.6%) | 0.019 | 1 (0.8%) | 3 (2.4%) | 0.342 |
| | Ostial lesion | 143 (19.6%) | 109 (18.9%) | 34 (22.1%) | 0.376 | 24 (20.2%) | 29 (23.0%) | 0.588 |
| | Bifurcation lesion | 123 (16.8%) | 97 (16.8%) | 26 (16.9%) | 0.983 | 18 (15.1%) | 23 (18.3%) | 0.512 |
| | Severe tortuosity | 58 (7.9%) | 48 (8.3% | 10 (6.5%) | 0.456 | 9 (7.6%) | 10 (7.9%) | 0.913 |
| | AHA/ACC type B2/C lesion | 340 (46.5%) | 267 (46.3%) | 73 (47.4%) | 0.803 | 57 (47.9%) | 59 (46.8%) | 0.866 |
| | Number of diseased vessels | | | | | | | | | single | 275 (37.6%) | 220 (38.1%) | 55 (35.7%) | 0.184 | 50 (42.0%) | 44 (34.9%) | 0.314 | | double | 274 (37.5%) | 222 (38.5%) | 52 (33.8%) | 41 (34.5%) | 42 (33.3%) | | triple | 182 (24.9%) | 135 (23.4%) | 47 (30.5%) | 28 (23.5%) | 40 (31.7%) |
| | Reference diameter (mm) | 2.45±0.41 | 2.31±0.26 | 3.15±0.26 | - | 2.45±0.23 | 3.16±0.27 | - |
| | Lesion length | 17.4±8.6 | 17.2±8.8 | 17.6±8.3 | 0.517 | 17.2±9.8 | 17.4±9.0 | 0.856 |
| | Degree of stenosis (%) | 84.7±11.8 | 84.9±11.9 | 83.9±11.5 | 0.429 | 84.0±14.9 | 84.6±10.6 | 0.738 |
| | DCBs used | 772 | 609 | 163 | - | 127 | 132 | - |
| | Predilatation | 721 (93.4%) | 571 (93.8%) | 150 (92.0%) | 0.428 | 120 (94.5%) | 121 (91.7%) | 0.372 |
| | Predilation device diameter (mm) | 2.19±0.42 | 2.00±0.23 | 2.50±0.61 | <0.001 | 2.15±0.32 | 2.59±0.50 | - |
| | Predilatation device length (mm) | 14.6±4.1 | 14.5±4.0 | 14.8±4.2 | 0.370 | 14.7±4.1 | 14.7±4.4 | 0.919 |
| | Predilatation pressure (atm) | 11.6±3.5 | 11.4±3.4 | 12.5±3.8 | 0.002 | 12.1±3.4 | 12.6±3.8 | 0.298 |
| | DCB diameter (mm) | 2.47±0.42 | 2.31±0.28 | 3.04±0.34 | 0.002 | 2.45±0.26 | 3.05±0.33 | - |
| | DCB length (mm) | 20.6±4.9 | 20.7±4.7 | 20.4±5.2 | 0.061 | 20.3±4.9 | 20.1±5.2 | 0.751 |
| | DCB inflation pressure (atm) | 9.2±2.8 | 9.1±2.7 | 9.5±3.1 | 0.493 | 9.3±2.8 | 9.7±3.1 | 0.434 |
| | DCB inflation time (sec) | 50.9±16.5 | 50.2±16.4 | 53.5±16.8 | 0.599 | 50.7±17.0 | 53.4±15.7 | 0.264 |
| | Additional stent per DCB | 46 (6.0%) | 33 (5.4%) | 13 (8.0%) | 0.221 | 9 (7.1%) | 10 (7.6%) | 0.880 |
| | Overall technical success per lesion | 765 (99.1%) | 604 (99.2%) | 161 (98.8%) | 0.627 | 127 (100.0%) | 130 (98.5%) | 0.164 |
| | Multivessel PCI, non-target lesions | 269 (36.8%) | 230 (37.8%) | 57 (35.0%) | 0.512 | 33 (26.0%) | 48 (36.4%) | 0.072 |
| | BVS used in non-target lesions | 8 (1.0%) | 7 (1.1%) | 1 (0.6%) | 0.548 | 0 (0.0%) | 1 (0.8%) | 0.326 |
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independent t-test, otherwise Chi 2 or Fisher’s Exact Test whenever applicable. |
