Safety and Long-Term Efficacy of Drug-Coated Balloon Angioplasty following Rotational Atherectomy for Severely Calcified Coronary Lesions Compared with New Generation Drug-Eluting Stents
Table 5
Pre- and postprocedural quantitative angiographic characteristics in the crude and matched cohorts.
DCB-iRA lesions
nDES-iRA lesions
P value
Crude cohorts
n=51
n=62
At PCI
Reference diameter (mm)
2.33±0.63
2.50±0.57
0.14
Lesion length (mm)
11.56±6.19
18.57±7.98
<0.001
MLD (mm)
Pre-intervention (mm)
0.86±0.38
0.91±0.40
0.49
Post-intervention (mm)
1.75±0.50
2.57±0.51
<0.001
Percent diameter stenosis
Pre-intervention (%)
62.27±13.31
64.70±15.39
0.38
Post-intervention (%)
22.86±10.11
9.59±6.10
<0.001
Acute Gain (mm)
0.90±0.39
1.66±0.53
<0.001
Rotablator burr size
Mean burr size (mm)
1.74±0.28
1.68±0.21
0.21
B/A ratio
0.78±0.17
0.70±0.14
0.006
At follow-up
MLD (mm)
1.68±0.63
2.03±0.84
0.015
% diameter stenosis (%)
29.01±20.25
25.12±23.56
0.36
Late lumen loss (mm)
0.08±0.43
0.54±0.80
<0.001
Loss index
0.05±0.48
0.33±0.45
0.002
Matched cohorts
n=26
n=26
At PCI
Reference diameter (mm)
2.46±0.64
2.37±0.39
0.53
Lesion length (mm)
15.01±6.67
15.77±7.25
0.70
MLD (mm)
Pre-intervention
0.94±0.36
0.86±0.34
0.42
Post-intervention
1.78±0.42
2.38±0.34
<0.001
Acute Gain (mm)
0.85±0.37
1.53±0.43
<0.001
Percent diameter stenosis
Pre-intervention (%)
60.78±13.27
65.48±15.44
0.24
Post-intervention (%)
24.10±10.00
9.80±6.46
<0.001
Rotablator burr size
Mean burr size (mm)
1.78±0.32
1.67±0.20
0.16
B/A ratio
0.74±0.11
0.72±0.11
0.45
At follow-up
MLD (mm)
1.69±0.57
1.87±0.60
0.29
% diameter stenosis (%)
29.52±17.62
23.81±20.52
0.29
Late lumen loss (mm)
0.09±0.48
0.52±0.63
0.009
Loss index
0.03±0.52
0.32±0.39
0.026
B/A ratio, burr-to-artery ratio; MLD, minimum lumen diameter; SD, standard deviation; PCI, percutaneous coronary intervention. Loss index; Late lumen loss / Acute gain.
