Research Article

Clinical Implications of Bifurcation Angles in Left Main Bifurcation Intervention Using a Two-Stent Technique

Table 5

Independent predictors of TLF in patients treated with the crush technique and T-stenting.

Univariable analysisMultivariable analysis
HR (95% CI) valueHR (95% CI) value

Crush Technique
Wide angle of LM-LAD (≥152°)2.50 (1.32–4.73)0.0052.57 (1.34–4.90)0.004
Wide angle of LAD-LCX (≥70°)1.01 (0.54–1.90)0.983
Diabetes mellitus1.18 (0.63–2.19)0.613
Dyslipidemia1.27 (0.67–2.40)0.461
Current smoker0.96 (0.46–1.99)0.907
Low LV systolic function (<50%)1.27 (0.62–2.58)0.509
Chronic kidney disease1.36 (0.53–3.47)0.521
Acute coronary syndrome1.20 (0.63–2.28)0.577
MV calcification1.55 (0.85–2.81)0.1521.60 (0.86–3.00)0.138
Long SB lesion (>5 mm)1.98 (0.92–4.26)0.0811.57 (0.70–3.51)0.275
High SYNTAX score (≥33)2.52 (1.16–5.46)0.0191.80 (0.97–3.33)0.062
Final kissing ballooning0.97 (0.41–2.34)0.953
IVUS-guided PCI0.95 (0.52–1.73)0.874
True bifurcation1.63 (0.82–3.22)0.1621.28 (0.63–2.61)0.501
2nd generation DES1.42 (0.73–2.76)0.308

T-stenting technique
Wide angle of LM-LAD (≥152°)0.85 (0.44–1.67)0.641
Wide angle of LAD-LCX (≥70°)1.53 (0.73–3.18)0.258
Diabetes mellitus0.97 (0.46–2.01)0.926
Dyslipidemia1.17 (0.59–2.33)0.656
Current smoker2.17 (1.04–4.52)0.0391.94 (0.82–4.58)0.129
Low LV systolic function (<50%)2.33 (1.01–5.37)0.0472.08 (0.86–5.00)0.103
Chronic kidney disease1.50 (0.46–4.91)0.506
Acute coronary syndrome0.83 (0.42–1.61)0.578
MV calcification2.31 (1.18–4.52)0.0142.78 (1.20–6.41)0.017
Long SB lesion (>5 mm)1.81 (0.85–3.87)0.1251.12 (0.47–2.70)0.796
High SYNTAX score (≥33)1.68 (0.34–3.41)0.912
Final kissing ballooning0.75 (0.18–3.17)0.694
IVUS-guided PCI0.94 (0.45–1.96)0.859
True bifurcation1.47 (0.64–3.36)0.365
2nd generation DES0.87 (0.44–1.72)0.697

CI, confidence interval; DES, drug-eluting stent; HR, hazard ratio; LAD, left anterior descending artery; LCX, left circumflex artery; LM, left main; LV, left ventricle; MV, main vessel; SB, side branch; TLF, target lesion failure.