Comparison of Instantaneous Wave-Free Ratio (iFR) and Fractional Flow Reserve (FFR) with respect to Their Sensitivities to Cardiovascular Factors: A Computational Model-Based Study

Figure 5

Comparisons of model-simulated aortic pressure wave and coronary arterial pressure wave distal to a 50% stenosis in mid-LAD and iFR/FFR (a∼d), flow wave in mid-LAD (e∼h), and poststenosis coronary microvascular resistance (i∼l) under control resting/hyperemic condition with those in the presence of severe AS (EOA_sys = 1.0 cm²) or increased coronary microvascular resistance (increased by 120% relative to the reference value).

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